可见,T细胞亚群的改变在SLE的发病中起到很大的作用,检测SLE患者外周血T淋巴细胞表型,对全面地了解机体的免疫状态,正确判断病情和指导临床
治疗有重要的意义。
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【参考文献】
[1]Tam EM,Cohen AS,Fries JF,et al.The 1982 revised criteria for the classification of systemic lupus erythematosus(SLE)[J].Arthritic Rheum,1982,25:1271.
[2]VitaliC,Bencivelli W,Lsenberg DA,et al.Disease zctivity in systemic lupus erythematosus:report of consensus study group of the European workshop for rheumatology research. II.Identification of the variables indicative of diseaseactivity and their use in the development of an activity score[J].Clin Exp Rheumatol,1992,10:341.
[3]Raziuddin S,Nur MA,AlWabel AA.Increased circulating HLADR+CD4+ Tcells insystemic lupus erythematosus:alterations associated with prednisolone therapy[J].Scand J Immunol,1990,31(2):139145.
[4]Maeda N,Sekigawa I,Iida N,et al.Relationship between CD4+/CD8+ T cellratio and T cell activation in systemic lupus erythematosus[J].Scand Rheumatd,1999,28(3):166.
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[5]张冬春,王林军,马安伦,等.SLE中的反抑制细胞与γδTCR阳性T细胞[J].风湿病学杂志,1997,2(4):1.
[6]蒋明,孙华瑜,朱立平,等.系统性红斑狼疮患者外周血中的T4+2H4+细胞的研究[J].中华内科杂志,1991,30(7):426.
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